As a result, activity throughout the sympathetic nervous system becomes prolonged and exaggerated. It also inhibits the normal reuptake of norepinephrine, dopamine, and serotonin, which are neurotransmitters that facilitate communications throughout your nervous system. HeartД¬ocaine is a stimulant that increases heart rate and blood pressure in the short term. If caught early, surgery may not be needed to repair the perforation. Septal perforations can be treated and reversed with medical attention. In more severe cases, a septal perforation can cause the nose to collapse, leading to a вЂsaddle noseвЂ™, which appears as an indent in the middle of your nose. If it completely dies, the cartilage that it supports also dies. Since oxygen cannot get to the tissues inside the septum, the lining begins to die. This condition manifests as a hole in the nasal septum, the soft partition located between your nostrils.Д¬ocaine use causes the blood vessels in your nose to constrict, cutting off the normal flow of blood to your nose. Long-term cocaine use can also cause a condition known as a вЂ Perforated SeptumвЂ™. People who primarily snort cocaine are susceptible to long-term damage to the nose. This can impact your self-insight and decision-making surrounding drug use, making it that much harder to seek treatment when you need it most. This, in turn, increases the risk of overdose.Д¬ocaine also changes the way your orbitofrontal cortex works. Prolonged and heavy cocaine use can also desensitize the receptors to the reward centers in your brain, meaning that it takes higher and/or more frequent doses to achieve the desired effect. It can impact the way your brain handles stress and make you more likely to seek drugs while you are stressed.

BrainД¬ocaine can change the way your brain works. The duration and severity of the effects largely depend on whether the drug was smoked, injected, or snorted. These effects will appear almost instantaneously after using cocaine and can take up to an hour to subside. There are many potential adverse effects of cocaine, from a fast or irregular heartbeat to increased blood pressure to restlessness, among others. Although using this drug may feel good due to the flood of dopamine in your brainвЂ™s reward circuit, there are many potential cocaine drug effects that can cause lasting damage to your body. It can be used in several ways and may be snorted, smoked, or injected directly into the veins.

Cocaine is a stimulant drug that is illegal for recreational use.

Can you shoot crack cocaine